https://ogma.newcastle.edu.au/vital/access/ /manager/Index en-au 5 Clinical validation of MR imaging time reduction for substitute/synthetic CT generation for prostate MRI-only treatment planning https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:53527 Wed 28 Feb 2024 15:53:26 AEDT ]]> Determination of acceptable Hounsfield units uncertainties via a sensitivity analysis for an accurate dose calculation in the context of prostate MRI-only radiotherapy https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:53776 Wed 28 Feb 2024 15:31:09 AEDT ]]> A deep learning model to generate synthetic CT for prostate MR-only radiotherapy dose planning: a multicenter study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:53856 Wed 28 Feb 2024 15:05:06 AEDT ]]> The impact of a regionally based translational cancer research collaborative in Australia using the FAIT methodology https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:54997 Wed 27 Mar 2024 16:38:22 AEDT ]]> Experimental evaluation of four-dimensional Magnetic Resonance Imaging for radiotherapy planning of lung cancer https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45273 Wed 26 Oct 2022 16:03:37 AEDT ]]> Optimisation and validation of an integrated magnetic resonance imaging-only radiotherapy planning solution https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45142 Wed 26 Oct 2022 15:43:14 AEDT ]]> Preliminary investigation of the effect of a-Si EPID spectral response on IMRT dosimetry https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:2877 Wed 24 Jul 2013 22:53:49 AEST ]]> Automatic radiotherapy delineation quality assurance on prostate MRI with deep learning in a multicentre clinical trial https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:43531 Wed 21 Sep 2022 11:32:29 AEST ]]> Can the Risk of Dysphagia in Head and Neck Radiation Therapy Be Predicted by an Automated Transit Fluence Monitoring Process During Treatment? A First Comparative Study of Patient Reported Quality of Life and the Fluence-Based Decision Support Metric. https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:43534 , weight change ΔW, ΔVROI, and Δϕn, were analyzed using the ranked-Pearson correlation. Results: No statistically significant correlation was found for age, gender and ΔW. was found to have clinically important correlation with functional MDADI (ρ = −0.39, P = 0.081). ΔVROI was found to have statistically significant correlation of 0.44, 0.47 and 0.44 with global, physical and functional MDADI (P-value < 0.05). Δϕn was found to have statistically significant ranked-correlation (−0.46, −0.46 and −0.45) with physical, functional and total MDADI (P-value < 0.05). Conclusion: A transit fluence based decision support metric (DSM) is statistically correlated with the dysphagia risk. It can not only be used as an early signal in assisting clinicians in the ART patient selection for replanning, but also lowers the resource barrier of ART implementation.]]> Wed 21 Sep 2022 11:32:28 AEST ]]> Comparing breast conservation surgery seromas contoured by radiation therapists versus those contoured by a radiation oncologist in radiation therapy planning for early-stage breast cancer https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38849 P = 0.65). Conclusion: BCS seromas contoured by RTs compared well with those contoured by an RO. This research has provided further evidence to support RTs in assuming additional contouring responsibilities in radiation therapy planning for patients with early-stage breast cancer.]]> Wed 16 Feb 2022 12:07:45 AEDT ]]> Real-Time Image Guided Ablative Prostate Cancer Radiation Therapy: Results From the TROG 15.01 SPARK Trial https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:42282 Wed 16 Aug 2023 14:37:30 AEST ]]> A Novel Vision Transformer Model for Skin Cancer Classification https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:53760 Wed 15 May 2024 16:00:49 AEST ]]> A system for real-time monitoring of breath-hold via assessment of internal anatomy in tangential breast radiotherapy https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45758 Wed 11 Jan 2023 10:15:35 AEDT ]]> Infections after fiducial marker implantation for prostate radiotherapy: are we underestimating the risks? https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27681 Wed 11 Apr 2018 13:22:02 AEST ]]> Visualising the urethra for prostate radiotherapy planning https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:49004 Wed 03 May 2023 12:17:09 AEST ]]> Real-time intrafraction prostate motion during linac based stereotactic radiotherapy with rectal displacement https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33946 Wed 02 Mar 2022 14:29:12 AEDT ]]> In vivo dosimetry in external beam photon radiotherapy: Requirements and future directions for research, development, and clinical practice https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:54059 Tue 30 Jan 2024 13:55:37 AEDT ]]> Non-contrast based approach for liver function quantification using Bayesian-based intravoxel incoherent motion diffusion weighted imaging: A pilot study https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:53472 Tue 28 Nov 2023 15:54:21 AEDT ]]> Predictive quality assurance of a linear accelerator based on the machine performance check application using statistical process control and ARIMA forecast modeling https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:39845 Tue 19 Jul 2022 08:45:26 AEST ]]> Optimisation of 2D U-Net model components for automatic prostate segmentation on MRI https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38709 Tue 18 Jan 2022 11:49:18 AEDT ]]> Insensitivity of machine log files to MLC leaf backlash and effect of MLC backlash on clinical dynamic MLC motion: An experimental investigation https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:52542 Tue 17 Oct 2023 10:18:54 AEDT ]]> EPID-based dosimetry to verify IMRT planar dose distribution for the aS1200 EPID and FFF beams https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29751 Tue 16 Mar 2021 10:50:28 AEDT ]]> Clinical target volume delineation quality assurance for MRI-guided prostate radiotherapy using deep learning with uncertainty estimation https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51626 Tue 12 Sep 2023 15:40:55 AEST ]]> Assessment of semi-automated stereotactic treatment planning for online adaptive radiotherapy in ethos https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51445 Tue 05 Sep 2023 17:55:17 AEST ]]> A multi-center prospective study for implementation of an MRI-only prostate treatment planning workflow https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:39881 Tue 04 Oct 2022 15:37:28 AEDT ]]> The first clinical implementation of a real-time six degree of freedom target tracking system during radiation therapy based on Kilovoltage Intrafraction Monitoring (KIM) https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:34638 Patient: A patient with prostate adenocarcinoma undergoing SBRT with 36.25 Gy, delivered in 5 fractions was enrolled in the study. 6DoF KIM technology: 2D positions of three implanted gold markers in each of the kV images (125 kV, 10 mA at 11 Hz) were acquired continuously during treatment. The 2D → 3D target position estimation was based on a probability distribution function. The 3D → 6DoF target rotation was calculated using an iterative closest point algorithm. The accuracy and precision of the KIM method was measured by comparing the real-time results with kV-MV triangulation. Results: Of the five treatment fractions, KIM was utilised successfully in four fractions. The intrafraction prostate motion resulted in three couch shifts in two fractions when the prostate motion exceeded the pre-set action threshold of 2 mm for more than 5 s. KIM translational accuracy and precision were 0.3 ± 0.6 mm, −0.2 ± 0.3 mm and 0.2 ± 0.7 mm in the Left-Right (LR), Superior-Inferior (SI) and Anterior-Posterior (AP) directions, respectively. The KIM rotational accuracy and precision were 0.8° ± 2.0°, −0.5° ± 3.3° and 0.3° ± 1.6° in the roll, pitch and yaw directions, respectively. Conclusion: This treatment represents, to the best of our knowledge, the first time a cancer patient’s tumour position and rotation have been monitored in real-time during treatment. The 6 DoF KIM system has sub-millimetre accuracy and precision in all three translational axes, and less than 1° accuracy and 4° precision in all three rotational axes.]]> Thu 24 Mar 2022 11:35:51 AEDT ]]> Assessment of the accuracy of truebeam intrafraction motion review (IMR) system for prostate treatment guidance https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38728 Thu 20 Jan 2022 13:36:08 AEDT ]]> Phase 2 multicenter study of gantry-based stereotactic radiotherapy boost for intermediate and high risk prostate cancer (PROMETHEUS) https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:34741 Thu 17 Feb 2022 09:29:26 AEDT ]]> Pseudo-CT generation for MRI-only radiotherapy: comparative study between a generative adversarial network, a U-Net network, a patch-based, and an atlas based methods https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38715 Mon 20 Nov 2023 15:50:10 AEDT ]]> Voxel-wise analysis for spatial characterisation of pseudo-ct errors in MRI-only radiotherapy planning https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:43841 Mon 20 Nov 2023 14:35:06 AEDT ]]> Computed tomography synthesis from magnetic resonance imaging using cycle Generative Adversarial Networks with multicenter learning https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:55076 Mon 08 Apr 2024 14:17:28 AEST ]]> Image synthesis for MRI-only radiotherapy treatment planning https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46392 Fri 25 Nov 2022 13:59:19 AEDT ]]> Fostering a culture of research within a clinical radiation oncology department https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46579 Fri 25 Nov 2022 13:39:41 AEDT ]]> Determination of hepatic extraction fraction with gadoxetate low-temporal resolution DCE-MRI-based deconvolution analysis: validation with ALBI score and Child-Pugh class https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51930 Fri 22 Sep 2023 11:07:30 AEST ]]> Determination of the electronic portal imaging device pixel-sensitivity-map for quality assurance applications. Part 1: Comparison of methods https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51889 Fri 22 Sep 2023 09:22:44 AEST ]]> Determination of the electronic portal imaging device pixel-sensitivity-map for quality assurance applications. Part 2: Photon beam dependence https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51888 Fri 22 Sep 2023 09:22:04 AEST ]]> Genitourinary Quality-of-Life Comparison Between Urethral Sparing Prostate Stereotactic Body Radiation Therapy Monotherapy and Virtual High-Dose-Rate Brachytherapy Boost https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:52691 Fri 20 Oct 2023 15:54:55 AEDT ]]> A Review of the Recent Progress on Crowd Anomaly Detection https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51078 Fri 18 Aug 2023 09:31:56 AEST ]]> Investigation of a water equivalent depth method for dosimetric accuracy evaluation of synthetic CT https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51714 Fri 15 Sep 2023 17:46:38 AEST ]]> Geometric uncertainty analysis of MLC tracking for lung SABR https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:39998 Fri 15 Jul 2022 11:01:56 AEST ]]> Effects of MR imaging time reduction on substitute CT generation for prostate MRI-only treatment planning https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:40333 Fri 08 Jul 2022 09:44:37 AEST ]]> First clinical experience with real-time portal imaging-based breath-hold monitoring in tangential breast radiotherapy https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51352 , per tangent were compared to the planned mLDs; differences between the largest and smallest observed () per tangent were calculated. Results: For 56% (162/288) of the tangents tested, were outside the tolerance window. All but one patient had at least one fraction showing this behaviour. The largest difference found between an and its planned mLD was −16.9 mm. The accuracy of patient positioning and the quality of marker-block-based DIBH guidance contributed to the differences. Fractions with patient position verification using a single EPID image taken before treatment showed a lower rate (34%), suggesting reassessment of setup procedures. Conclusions: Real-time treatment monitoring of the internal anatomy during DIBH delivery of tangential breast RT is feasible and useful. The new system requires no additional radiation for the patient.]]> Fri 01 Sep 2023 13:36:10 AEST ]]>